MEDizzy
MEDizzy
Andy Wells
Andy Wellsover 4 years ago
Lichen Planus

Lichen Planus

A 69-year-old man presented to the dermatology clinic with a 2-month history of a pruritic rash. The rash had first appeared on his right wrist and within 2 weeks had spread to his arms, legs, and trunk. His medical history was notable for chronic hepatitis C virus (HCV) infection, for which he had completed a 12-week course of elbasvir and grazoprevir 3 months before the onset of the rash. On examination, numerous purple papules were noted on the anterior surface of the forearms (Panel A) and the dorsal surface of the hands (Panel B) as well as on the trunk and legs. Several lesions showed a fine reticulate pattern of dots and lines, called Wickham’s striae. Biopsy of a lesion revealed hyperkeratosis, wedge-shaped hypergranulosis, sawtooth rete pegs, and bandlike lymphocytic inflammation — findings confirming the diagnosis of lichen planus. Although the cause of lichen planus has not been established definitively, it is thought to be an autoimmune disease. Lichen planus has a known association with HCV infection. In this patient, the association between HCV infection, which had been treated, and the later eruption was unclear. Topical or intralesional glucocorticoids may be used in primary treatment, with ultraviolet light therapy and oral immunosuppressive agents reserved for more extensive cases. This patient was treated with topical clobetasol and narrow-band ultraviolet B therapy, and a reduction in lesions occurred within 1 month after the start of treatment. Source: nejm.org

73
Other commentsSign in to post comments. You don't have an account? Sign up now!
almost 7 years ago

Weakly itraconazol. Terbenafine & lcz per day , ketonazal lotion,.

almost 7 years ago

Amorolfin 0.25% cream

15 days ago

I was diagnosed as a Hepatitis B carrier in 2015, with early signs of liver fibrosis. At first, antiviral medications helped control the virus but over time, resistance developed, and the effectiveness faded. I began to lose hope. In 2021, I discovered NaturePath Herbal Clinic despite my skepticism, I decided to give their herbal treatment a try.To my surprise, after just six months, my blood tests came back negative for the virus.It was nothing short of life-changing.I never expected such incredible results from a natural treatment. But it not only cleared the virus it restored my hope, my health, and my peace of mind.If you or someone you know is battling Hepatitis B, I truly encourage you to explore the natural healing path offered by NaturePath Herbal Clinic. It gave me a second chance and it might do the same for you.www.naturepathherbalclinic.com info@naturepathherbalclinic.com

Recent MCQs















Show more MCQs

Recent flashcard sets















Show more flashcards