Dr. Fatemeh Kourkinejadover 6 years ago
Is it contraindicated to use aminocaproic acid or tranexamicacid to treat hematuria? Please let me know, what are you thinking.Thanks.
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over 6 years ago
Tranexamic acid produces antifibrinolytic effects via complex interactions with plasminogen, displacing plasminogen from the fibrin surface. Chronic renal impairment is considered a relative contraindication to use of tranexamic acid due to reports of ureteric clots and acute renal failure from cortical necrosis.
over 6 years ago
In patients with upper urinary tract bleeding, AMICAR (aminocaproic acid) administration has been known to cause intrarenal obstruction in the form of glomerular capillary thrombosis or clots in the renal pelvis and ureters.
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