The prognosis for AIDS has greatly improved since the introduction of HAART. The latter is the term given to the use of combinations of antiretroviral drugs, such as two nucleoside reverse transcriptase inhibitors (nRTIs) plus one or two protease inhibitors, or two nRTIs plus a non-nucleoside transcriptase inhibitor. All these drugs are capable of causing a wide variety of adverse effects and compliance may be unpredictable