Doctors may refer to urticaria as either: acute urticaria – if the rash clears completely within 6 weeks chronic urticaria – in rarer cases, where the rash persists or comes and goes for more than 6 weeks, often over many years A much rarer type of urticaria, known as urticaria vasculitis, can cause blood vessels inside the skin to become inflamed. In these cases, the weals last longer than 24 hours, are more painful, and can leave a bruise.