Notice how both kidneys demonstrate a large number of cysts of variable size (from a few mm to many cm), which are filled with fluid of variable colour - from clear or straw coloured to altered blood or chocolate coloured to purulent when infected. In Polycystic kidney disease, the clusters of fluid-filled sacs, or cysts, interfere the kidneys ability to filter waste products from the blood. The growth of cysts causes the kidneys to become enlarged and can lead to kidney failure. The disease frequently affect the kidneys, although patients may develop cysts in other organs such as liver, pancreas, ovaries and spleen. Furthermore, it may even affect the heart or brain. If it affects the patient’s brain, it can hence lead aneurysm. If affects his heart, then the valves may become floppy leading heart murmur. Frequent complications are dangerously high blood pressure (hypertension), pain in the back or sides, blood in the urine (hematuria), recurrent urinary tract infections, kidney stones, and heart valve abnormalities.A non-invasive, reliable and inexpensive diagnosis is made by ultrasound. There's currently no cure for PKD, but current treatment to manage problems caused by the condition are dialysis and transplant.