Premature Ventricular Complexes (PVCs) are extra heartbeats that originate in the ventricles, the lower chambers of the heart, and disrupt the normal heart rhythm. While often harmless and common, even in healthy individuals, frequent or persistent PVCs can be a cause for concern, especially if there is underlying heart disease. What are PVCs? PVCs are extra heartbeats that occur earlier than the next expected heartbeat in the normal rhythm. They are caused by an electrical impulse originating in the ventricles, rather than the sinoatrial node (the heart's natural pacemaker). PVCs can be felt as a skipped beat, a fluttering, or a strong beat followed by a pause.