Menkes syndrome is a neurodegenerative disorder. It causes brain and cognitive (thinking) problems that worsen over time. Children and adults with Menkes disease may have: Brain bleeding problems, such as subdural hematomas. Bulging pouches in bladder or digestive tract walls (diverticulosis). Excessive small bones (wormian bones) in their skull. Loss of coordinated movement (motor skills). Low bone density (osteoporosis) that can lead to bone fractures. Twisted blood vessels (arterial tortuosity syndrome). If children experience brain bleeding and broken bones, healthcare providers might worry about possible child abuse. Talk with your healthcare provider about Menkes disease testing if you know your child lives in a safe environment but has these symptoms.