Less Common Liver Enzymes That Cause Medical Problems AST and AKT are the most commonly known liver enzymes which are observed in multiple diseases. Other liver enzymes include; • Alkaline phosphatase – Elevated level indicates biliary injury, biliary obstruction and gallstones, use of certain medicines, bone diseases • 5'-nucleotidase ("5 prime" nucleotidase) – Elevated level indicates biliary injury, biliary obstruction and gallstones • Lactate dehydrogenase (LDH) – Elevated level indicates biliary disease and inflammation of other tissues • Gmma-glutamyl transpeptidase (GGT) – Elevated level indicates biliary injury, biliary obstruction and gallstones