Lumbar puncture is absolutely contraindicated in the following cases: - Infection at the site of lumbar puncture - Mass occupying lesion causing increased intracranial pressure - Mass at the site of lumbar puncture - Trauma to lumbar vertebrae Reference: https://accessemergencymedicine.mhmedical.com/content.aspx?bookid=991§ionid=55139110#:~:text=Absolute%20contraindications%20for%20performing%20a,or%20mass%20to%20lumbar%20vertebrae. Image via: https://en.wikipedia.org/wiki/CSF_tap_test