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Ladli Samudrealmost 4 years ago
What is the role of viral replication in the pathophysiology of human parainfluenza virus (HPIV) infection?
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almost 4 years ago
Viral Replication in Pathophysiology of HPIV In viral replication of HPIV, virus fuses with host cell lipid membrane. Now, nucleocapsid forces outside into the cytoplasm of cell. Therefore, transcription takes place in cytoplasm mediated by virus-specific RNA-dependent RNA polymerase. Cellular ribosomes translate viral mRNAs into viral proteins. The accessory viral proteins with anti-interferon properties decide the pathogenicity of HPIV.
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