Debridment in HSV Keratitis Debridment is the practice of removing foreign objects or damaged tissue from a wound. In HSV keratitis, debridment may be harmful. The use of sharp objects, strong chemicals and cryotherapy produce difficulty as it may cause damage to the Bowman layer and other unnecessary damage. In the process of debridement, a cotton-tipped applicator is used to apply topical anesthesia and brush the epithelial lesions. It is a convenient and effective technique which facilitates rapid healing within 48 hours. To prevent recurrent lesions after healing use of topical antiviral for 7-10 days after debridement is recommended.