This video edit shows the a hybrid approach for the transanal resection of a very large low rectal polyp. It is associated with a text under submission for publication in the journal Colorectal Disease. Click Subscribe to this channel for the most up to date content. Authors: Mr David RC James PhD FRCS, Miss Sarah Goodbrand MD FRCS, Miss Pam Sivathondan MD FRCS, Mr Chris Cunningham MD FRCS, Mr Roel Hompes MD. Oxford Radcliffe University Hospitals, Oxford, United Kingdom. Video associated with Colorectal Disease Journal (published by Wiley and associated with the Association of Coloproctology Great Britain and Ireland (ACPGBI), European Society of Coloproctology (ESCP) and Spanish Society of Coloproctology (SSC).