MEDizzy
MEDizzy
Jawad Shirzad
Jawad Shirzad over 7 years ago

What is Celiac Disease????

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about 7 years ago

Fusion of villi and loss in absorptive area due to autoimmune disease

about 7 years ago

Celiac disease, is a long-term autoimmune disorder that primarily affects the small intestine. Coeliac disease is caused by a reaction to gluten, which are various proteins found in wheat and in other grains such as barley and rye.

about 7 years ago

Upon exposure to gluten, an abnormal immune response may lead to the production of several different autoantibodies that can affect a number of different organs. In the small bowel, this causes an inflammatory reaction and may produce shortening of the villi lining the small intestine (villous atrophy). This affects the absorption of nutrients, frequently leading to anaemia.

about 7 years ago

Diagnosis is typically made by a combination of blood antibody tests and intestinal biopsies, helped by specific genetic testing. Making the diagnosis is not always straightforward. Frequently, the autoantibodies in the blood are negative, and many people have only minor intestinal changes with normal villi.

about 7 years ago

The classic symptoms of coeliac disease include pale, loose, and greasy stool (steatorrhoea) and weight loss or failure to gain weight. More common symptoms are subtle or primarily occur in organs other than the bowel itself. It is also possible to have coeliac disease without any classic symptoms whatsoever. This represents at least 43% of the cases in children. Many adults with subtle disease only have fatigue or anaemia.

about 7 years ago

At present, the only effective treatment is a lifelong gluten-free diet. No medication exists that prevents damage or prevents the body from attacking the gut when gluten is present. Strict adherence to the diet helps the intestines heal, leading to resolution of all symptoms in most cases.

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