Hi. I have a question, how can anti arrhythmic drugs target the myocardial cells without affecting other cells in the body, since most of those drugs are ion channel blockers and almost every cell in the body has a variety of ion channels ?
I think the best way is to use beta blockers that are specific for myocardial cells.
Hmm, but in sometimes you can’t diagnose the type of arrhythmia on ECG, or you are in an emergent case and use for example Amiodarone, now how Amiodarone gonna target myocardial cells? I think the answer is that it targets active and abnormal ion channels, which is in this case, the myocardial cells, but I’m not sure if the answer 😓