Bubonic plague
Bubonic plague is one of three types of plague caused by bacterium Yersinia pestis. One to seven days after exposure to the bacteria, flu-like symptoms develop. These include fever, headaches, and vomiting. Swollen and painful lymph nodes occur in the area closest to where the bacteria entered the
at 28 degrees the bacteria ( Y.pestis)produce the coagulase in the flea that closes the periventricule of the flea. The fleas gets hungry so she suck human blood and regurgitate the bacteria in the human blood wher the temperature is 37 degrees so caogulase ruptures(cause it’s only produced at 28 degrees).The commenset outcome is the bubonic plague where there is a formation of a bubo=enlarged of the lymph node (lymphadenopathy) typically in the axilla and the groin region which is painful. The desease progressives into a bacterimia with septicemia , the first signs :fever, GI disturbance (vomiting,nausea, boody diarrhea).The person can develop a delirium if the CNS is affected. when the lungs are involved we have a secondary pneumonic plague .Death occurs whit in 2-6 days if no treatment ( streptomycin +or - tetracycline) Note : everything releated to plague is hemmoragic
it’s less common than before but once a person is infected the transmission is very fast so we recommend a vaccine for travelers when they go to endemic area
