Enamel microstructure showing a schematic diagram of keyhole-shaped enamel prisms or rods about 5 μm in diameter (B). Atomic force microscopy (AFM) images showing prism cross sections in A and along axes of the prisms in C. Crystallite orientation deviates in the inter-rod and tail area, and the organic content increases in the inter-rod area. (Modified from Habelitz S, et al: Arch. Oral Biol. 46, 173-183, 2001.)