The treatment for polyphagia depends on the underlying cause. It usually goes away once the condition that caused it is properly treated. For example, treatment for Type 1 diabetes involves lifelong insulin injections and managing blood sugar levels. Hypoglycemia must be treated by eating or drinking sugar (glucose) or with a glucagon injection or nasal powder. Treatment for hyperthyroidism may involve antithyroid medication, radioactive iodine or surgery. If a medication is causing polyphagia, your healthcare provider may switch the medication, if possible.