Baby acne is a temporary condition that goes away without treatment. Every baby’s skin is different, so if their healthcare provider recommends treatment, it could include: An antifungal cream like ketoconazole. A low-potency topical steroid like hydrocortisone. You can apply these to your baby’s skin as you would a lotion or moisturizer. Follow your healthcare provider’s instructions on how often you should apply these medications to your baby’s skin.