Common nephrotic syndrome symptoms include: Large amounts (greater than 3.5 grams) of the protein albumin in your pee (albuminuria). High fat and cholesterol levels in your blood (hyperlipidemia). Swelling (edema), usually in your legs, feet or ankles. Swelling may also occur in your hands or face. Low levels of albumin in your blood (hypoalbuminemia). Loss of appetite. Feeling unwell or sick. Abdominal pain (pain anywhere from your ribs to your pelvis). Foamy pee.