Physical exam to diagnose hypertriglyceridemia Your healthcare provider will perform a physical exam to learn more about your health. They’ll also talk with you about your: Family history of heart disease, high cholesterol and high triglycerides. Lifestyle factors (like alcohol and tobacco use). Medical history. Medications you’re taking. This information will help your provider identify possible causes for hypertriglyceridemia. It’ll also help your provider learn your risk for cardiovascular disease. Testing to diagnose hypertriglyceridemia A common blood test called a lipid panel diagnoses hypertriglyceridemia. This test measures your triglycerides and your cholesterol levels. Your provider may ask you to fast for 10 to 12 hours before your blood test. Fasting means you should consume no foods or drinks except water. Be sure to follow your provider’s instructions so you receive the most useful results