Blood tests Sometimes genetic testing Blood tests help doctors diagnose Wiskott-Aldrich syndrome. Theses tests are used to determine: The total number of white blood cells and the percentages of the different types of white blood cells The number of platelets Levels of immunoglobulins The quantity and type of antibodies produced in response to vaccines and other substances that usually trigger an immune response (antigens) T-cell function Genetic testing may be done to identify the mutation and confirm the diagnosis. It is recommended for close relatives. If Wiskott-Aldrich syndrome is diagnosed, doctors monitor the person by regularly doing blood tests to check for leukemia and lymphoma.