People with monkeypox get a rash that may be located on or near the genitals (penis, testicles, labia, and vagina) or anus (butthole) and could be on other areas like the hands, feet, chest, face, or mouth. The rash will go through several stages, including scabs, before healing. The rash can initially look like pimples or blisters and may be painful or itchy. Other symptoms of monkeypox can include: Fever Chills Swollen lymph nodes Exhaustion Muscle aches and backache Headache Respiratory symptoms (e.g. sore throat, nasal congestion, or cough) You may experience all or only a few symptoms Sometimes, people have flu-like symptoms before the rash. Some people get a rash first, followed by other symptoms. Others only experience a rash.