What are the symptoms of goiter? The size of a goiter can range from very small and barely noticeable to very large. Most goiters are painless, but if you have thyroiditis (an inflamed thyroid gland), it can be painful. The main symptoms of goiter include: A lump in the front of your neck, just below your Adam's apple. A feeling of tightness in your throat area. Hoarseness (scratchy voice). Neck vein swelling. Dizziness when you raise your arms above your head. Other, less common symptoms include: Difficulty breathing (shortness of breath). Coughing. Wheezing (due to squeezing of your windpipe). Difficulty swallowing (due to squeezing of your esophagus). Some people who have a goiter may also have hyperthyroidism (overactive thyroid). Symptoms of hyperthyroidism include: Rapid heart rate (tachycardia). Unexplained weight loss. Diarrhea. Sweating without exercise or increased room temperature. Shaking. Agitation. Some people with goiter may also have hypothyroidism (underactive thyroid). Symptoms of hypothyroidism include: Fatigue (feeling tired). Constipation. Dry skin. Unexplained weight gain. Abnormal menstruation (periods