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Sheeza Basharat
Sheeza Basharat7 months ago
Angioedema of the lips!

Angioedema of the lips!

Angioedema is a result of the fast onset of an increase in local vascular permeability and leakage in subcutaneous or submucosal tissue. Histamine and bradykinin are the most recognized vasoactive mediators known to be critical in the pathologic process. It often involve the lip, eyes, and face. However, it may affect the respiratory and gastrointestinal mucosa. Laryngeal edema causing laryngospasm and airway obstruction is by far the most life-threatening complication. In rapid airway compromise, local anaphylaxis protocol (epinephrine) should be followed and mechanical intervention may be needed, either by intubation or cricothyrotomy/tracheotomy. The need for intubation is significantly greater with presentations of laryngeal or pharyngeal involvement versus swelling of the lips and face. By:

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