Monro Kellie doctrine describes properties of skull and the structures residing within. Since cranium is a rigid cavity, hence contents within the cranium should be controlled in such a way that intracranial pressure remains within normal range. Any expanding mass within a cranium can displace fluid, cerebrospinal fluid, and venous blood from the cranium so as to maintain the intracranial pressure. If intracranial pressure increases from the normal range, it can cause hydrocephalus and herniation. Reference: Bailey and Love's Short Practice of Surgery Image via: https://teachmesurgery.com/neurosurgery/flow-and-pressure/monro-kellie-doctrine/