Anahita khannaalmost 7 years ago
What is the mechanism of action of fibrinolytic drugs?
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Plasminogen is converted into plasmin by tissue plasminogen activator(tpa)..plasmin will cause degradation of insoluble fibrin polymers into soluble fibrin monomers...Fibrinolytics like streptokinase,urokinase,reteplase,alteplase are stimulants(+)of tpa...so cause more activation of plasmin
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