Recessive dystrophic epidermolysis bullosa (RDEB)
Generalized recessive dystrophic epidermolysis bullosa represents one of the more debilitating forms of epidermolysis bullosa. It is characterized by generalized cutaneous and mucosal blistering with even minor trauma. Secondary infections are often a problem because of the large surface areas that may be involved. The hands and feet function is often greatly diminished because of the repeated episodes of cutaneous breakdown and healing with scarring, resulting in fusion of the fingers into a mittenlike deformity as shown. The oral problems are no less severe. Bulla and vesicle formation is induced by virtually any food having some degree of texture. Even with a soft diet, the repeated cycles of scarring often result in microstomia and ankyloglossia may occur. credits: Brad W. Neville, Douglas D. Damm, Carl M. Allen, Angela C. Chi - Oral and Maxillofacial Pathology-Saunders (2015) https://images.app.goo.gl/9deFZxvJy8PbgeXR7
