Sertraline Oral belongs to the class of Selective Serotonin Reuptake Inhibitors (SSRIs). This over-the-counter medicine is prescribed for the treatment and management of mental disorders such as Obsessive Compulsive Disorder (OCD), Major Depressive Disorder (MDD), Post-Traumatic Stress Disorder (PTSD), Pre-Menstrual Disorder (PMS), Social Anxiety Disorder, Panic Disorder and other depression-associated disorders. The side effects of Sertraline Oral include - Nausea and vomiting - Loss of appetite - Loss of libido and failure to ejaculate - Urine leakage and frequent urination - Heavy menstruation - Agitation - Tiredness - Trouble in sleeping - Suicidal thoughts Sertraline Oral interacts with the following drugs. - MonoAmine Oxidase Inhibitors (MAOIs) e.g. Phenelzine, isocarboxazid - NSAIDs e.g. Ibuprofen, Naproxen - Tricyclic Anti-Depressants e.g. Amitriptyline, Imipramine