Most expected side effects of Biological Therapy are - Allergic hypersensitivity - Injection site reactions - Infusion reactions - Nausea and vomiting - Fever and chills - Weakness and fatigue - Rash - Itching - Weakness - Cough - Constipation - Shortness of breath - High blood glucose level - Muscle ache and pain - Headache - Back pain - Loss of appetite - Insomnia - Increased triglyceride level - Dizziness - Hypotension i.e. low blood pressure - Bleeding - Hepatitis - Anemia - Hypothyroidism - Leukopenia i.e. low white blood cell count