Sheeza Basharatover 3 years ago

Lamellar Ichthyosis

Lamellar ichthyosis is a rare genetic condition that affects the skin.Infants affected by lamellar ichthyosis are generally born with a shiny, waxy layer of skin (called a collodian membrane) that is typically shed within the first two weeks of life. The skin beneath the collodian membrane is red and scaly. Lamellar ichthyosis is generally inherited, autosomal recessive disorder.Approximately 90% of cases are caused by mutations in the TGM1 gene. Symptoms include palmoplantar hyperkeratosis,nail abnormalities, respiratory problems,ectropion, lips that turn outwards, and hair loss. Unfortunately, there is currently no cure for lamellar ichthyosis. Management is generally supportive and based on the signs and symptoms present in each person. Credits: https://rarediseases.info.nih.gov/diseases/10803/lamellar-ichthyosis#:~:text=Lamellar%20ichthyosis%20is%20a%20rare,membrane%20is%20red%20and%20scaly. Image via : https://www.instagram.com/p/CD5gX5mBUOn/?igshid=16j08dt6sct6u