Calcinosis in Systemic Sclerosis
A 77-year-old right-handed woman with limited cutaneous systemic sclerosis presented to the rheumatology clinic with a 2-year history of slowly progressive, painful swelling of her fingertips. On physical examination, the patient had telangiectases on her face and thorax and thickening of the skin on her right hand, both forearms, and face, as well as soft-tissue swelling of the tips of the fingers of both hands (Panels A and B). Findings on capillaroscopy were notable for disorganization of capillaries, avascular areas, and the presence of enlarged capillaries. A radiograph of the hands showed calcifications near the distal phalanx of the first, second, and third fingers of the right hand and the first finger of the left hand (Panel C), which were consistent with calcinosis, a manifestation of limited cutaneous systemic sclerosis. These calcium deposits may grow, ulcerate, and become infected. Despite trials of multiple medications, the patient had progressive pain and numbness in her fingers, with increasing difficulty handling objects, and was referred for surgical evaluation regarding excision of the lesions.
Abdominal aortic aneurysmEar injury Cuts, fractures and blunt force trauma can cause ear injury. If damage is severe, surgery may be necessary to address the problem. This may include surgery to preserve hearing or cosmetic surgery to improve the appearance of your ear.Ear tumors Ear tumors may be benign (noncancerous) or malignant (cancerous). Types of noncancerous ear tumors include keloids, sebaceous cysts, osteomas and exostoses (bone growths). Noncancerous ear tumors usually require surgical removal. Cancers that can affect your ears include melanoma, basal cell carcinoma and squamous cell carcinoma. Treatment for these conditions depends on several factors, including the type and stage of cancer, and whether or not it has spread to other parts of your body.First Sickle Cell Gene TherapyMental and physical health are interconnected. We, as a society, need to work on emphasizing the importance of the two. This would prevent people developing physical and mental diseases at earlier and earlier ages.Treatment of degenerative joint diseaseGet Glowing Skin and Clear Face