Dr. Sáïshă about 5 years ago
Learning Pharma with spidey 🕸
Pilocarpine uses- Pilocarpine is a medication used to reduce the IOP and treat dry mouth (xerostomia as in Sjogren's syndrome). Mechanism of action- ⚒ Pilocarpine is a miotic that acts on the ciliary muscle and causes it to contract. When the ciliary muscle contracts, it opens the trabecular meshwork through increased tension on the scleral spur. This action facilitates the rate that aqueous humor leaves the eye, to decrease the intraocular pressure. Side effects - 💉💊 As pilocarpine is a cholinergic, the side effects are supposed to be "leaky" i.e., sweating, nausea, runny nose, chills, flushing, polyurea, dizziness, weakness, diarrhea, and blurred vision may occur.
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🍄 Commonly noticed Triads; Pentads🍚🍚 1. Hutchinson's Triad (congenital syphilis): - Hutchinson's teeth (notched incisors) - Interstitial keratitis - Deafness due to involvement of the eighth cranial nerve 2. Charcot's Triad(for cholangitis): - Jaundice - Fever with chills - Right upper quadrant pain 3. Samter's triad -bronchial asthma -nasal polyps - aspirin intolerance 4. Triad of O'Donoghue (or unhappy triad, often seen in sports injuries, especially knee injuries): - ACL (anterior cruciate ligament) tear - MCL (medial collateral ligament) tear - Medial meniscus tear 5. Beck's Triad (cardiac tamponade): - Distant/muffled heart sounds - Increased jugular venous pressure - Hypotension 6. Saint's Triad: - Gallstones - Diverticulosis - Hiatal hernia 7. Whipple's Triad: - Symptoms of hypoglycemia - Documented low blood sugar - Relief of symptoms after glucose administration 8. Cushing's Triad (seen in increased intracranial pressure): - Hypertension - Bradycardia - Irregular or abnormal respirations 9. Virchow's Triad(risk factors for thrombosis): - Endothelial injury - Stasis or turbulent blood flow - Blood hypercoagulability 10. Triad of Alport Syndrome: - Hematuria - Sensorineural hearing loss - Ocular abnormalities 11. Reynold's Pentad (an extension of Charcot's Triad for advanced cholangitis): - Jaundice - Fever with chills - Right upper quadrant pain - Septic shock - Mental confusion
🍄 Commonly noticed Triads; Pentads🍚🍚 1. Hutchinson's Triad (congenital syphilis): - Hutchinson's teeth (notched incisors) - Interstitial keratitis - Deafness due to involvement of the eighth cranial nerve 2. Charcot's Triad(for cholangitis): - Jaundice - Fever with chills - Right upper quadrant pain 3. Samter's triad -bronchial asthma -nasal polyps - aspirin intolerance 4. Triad of O'Donoghue (or unhappy triad, often seen in sports injuries, especially knee injuries): - ACL (anterior cruciate ligament) tear - MCL (medial collateral ligament) tear - Medial meniscus tear 5. Beck's Triad (cardiac tamponade): - Distant/muffled heart sounds - Increased jugular venous pressure - Hypotension 6. Saint's Triad: - Gallstones - Diverticulosis - Hiatal hernia 7. Whipple's Triad: - Symptoms of hypoglycemia - Documented low blood sugar - Relief of symptoms after glucose administration 8. Cushing's Triad (seen in increased intracranial pressure): - Hypertension - Bradycardia - Irregular or abnormal respirations 9. Virchow's Triad(risk factors for thrombosis): - Endothelial injury - Stasis or turbulent blood flow - Blood hypercoagulability 10. Triad of Alport Syndrome: - Hematuria - Sensorineural hearing loss - Ocular abnormalities 11. Reynold's Pentad (an extension of Charcot's Triad for advanced cholangitis): - Jaundice - Fever with chills - Right upper quadrant pain - Septic shock - Mental confusion