Polyarterities Nodosa is an autoimmune condition causes inflammation to small to medium sized blood vessels. PAN mostly affects major organs such as kidney(79%), heart, liver, and g.i.t. Risk factors for developing PAN are middle aged adults, active patients of hepatitis B & C. Symptoms occurs according to the damaged organ. Evaluation is by physical examination, biopsy, and arteriogram. Treatment is by steroids eg. Prednisone, and Cyclophosphamide.