Please identify which of the following is true with regard to pubertal development. A Pregnancy is not possible until regular menstruation occurs. B Adrenarche is the beginning of breast development. C Menarche, or onset of menstruation, is the first manifestation of puberty in the female. D Development of a menstrual cycle is dependent upon GnRH pulses increasing in amplitude and frequency.
The right answer is D. A is false as pregnancy is possible once menarche is achieved. However. early cycles may be irregular and anovulatory. Adrenarche is the onset of growth of pubic hair. Menarche is usually the last manifestation whereas development of the breast bud is the first (thelarche)