Hello doctors ! Plz help me with this ! .. Does the elasticity of the vessel wall affect the peripheral resistance ?? And what does peripheral resistance express exactly ??
A few things (very simplified) MAP = CO x TPR CO = cardiac output, MAP = mean arterial pressure (average pressure throughout a cardiac cycle) and TPR = total peripheral resistance. Think about peripheral resistance as “how hard the vessels push back on the heart”. If the vessels are elastic and able to accommodate, they will stretch (or relax) to accomodate the cardiac output. If the vessel walls are stiff (for example due to atherosclerotic changes) and unable to stretch/relax then. In a person with low TPR (healthy, stretchy/relaxable vessels), a rise in cardiac output will cause a relatively low rise in MAP (see the equation). When resistance is high, the same rise in cardiac output will cause a bigger jump in MAP. More importantly, as cardiac output must be maintained to provide adequate perfusion, a rise in peripheral resistance (due to loss of adequate accomodation of vessels for multiple reasons as discussed) results in an increase in MAP I.e higher blood pressure.
If increased peripheral resistance there can be loss of elasticity of vessles
So basically loss of elasticity can cause increase in PR leading to increase in BP
Of Course yes as arterioles is most vassels have elastic tissue in their wall
Yes elasticity affects the vessel walls...actually both are related such that increase in blood pressure , leads to vasodilation which decreases peripheral resistancse..leads to increase in systollic BP and decreasse in dystollic BP but mean arterial BP remains normal
