Various species of bacterial pathogens have become resistant to most of the antibotics due to antibiotic resistance generesidimg on extra chromosomal gene material and facilitating their horigental gene transfer scientifically it is termed as multi drug resistance bacteria . some examples of it are :- Enterococcous faecium , Vancomycin resistant staphylococcousa aureous. My aim is to discuss some option for the treatment and theraptic option for antibiotic resistance bacteria or ( superbug). In this context using of bacteriophage therapy as a method to kill antibiotic resistance bactereia . it will be a revolution ion both medical and industrial area. since earlier time a number of antibiotic resistance bacteria have been reported .group of such bacteria commonly pronounced as ESKAPE stand.some of these are enterococcous fascium ,pseudomonas aeruginosa and eschericia coli..Recently ,In new delhi metallo beta lactamase-1 containig antibiotic resistant feature have been identified. we can use bacteriophaage for the killing of antibiotic resistant bacteria.Bacteriophage are the virous that kills bacteria . bacteriophage was discovered in 1915 by british microbiologist felix twort .these are virus that infact and can kill kill bacteria . herelle systematically described the nature of bacteriophage and explored their ability to funguction as a therauptic agent . bacteriophage are highly specific ,they attack only host bacterial cellwithout any affect on normal micro flora . bacteriophage appear to evolve with bacteria as they are ubiquitous in nature . the increasing antibiotic resistance is one of the reason is one of the reason for growing intreswt in theraptic use of bacteriophage. Phages countinue to used for bacterial infection in place of antibiotics,in soviet union and eastern Europe . since more then eighty years ,phage therapy was used as bio-agent for the treatment of bacterial infection. Appearance of antibiotic resistance bacteria is a great challenge. Use of bacteriophage to kill antibiotic resistance bacteria is one of our best known arm to fight with challenges of antibiotic resistance bacteria .
This is so true. I have done research in this using E. Coli and Psuedemonas. And the phases were very effective. I ran a series of tests based on ability of phage mortality in varying temperatures and the success rate of lysis if only infected cells were astronomical. This is definitely a way to use what is already in our system to boost our natural ability to fight various infectious diseases.
