Dr Vijay Sharma over 6 years ago

Extensive dermal necrosis in the pre-irradiated scapular region about three weeks after the second dose of pemetrexed.

45 yrs female Conclusion: To the best of our knowledge, we present the first case of a patient with severe soft tissue necrosis in a pre-irradiated area after pemetrexed therapy. We believe that physicians treating patients with pemetrexed should be aware of the severe, possibly life-threatening effects that may be induced by pemetrexed after previous radiation therapy.