Purpura fulminans in a patient with strep pneumonia bacteremia!!
He was found down in a halfway house with altered mental status. Purpura fulminans is due to a rare, rapidly progressive, and often fatal syndrome of intravascular thrombosis and hemorrhagic infarction of the skin that is rapidly progressive and is accompanied by dermal vascular collapse and disseminated intravascular coagulation. It manifests as blood spots, bruising, and discoloration of the skin. It may occur in individuals with dysfunction of the protein C anticoagulant system, with acute severe infection, or idiopathically without any coagulation dysfunction or infection. Purpuric lesions were seen over many different skin sites, including the perineal region, the flexor surface of the thighs, and abdominal skin Skin lesions soon enlarge and become vesiculated, producing hemorrhagic bullae with subsequent necrosis and black eschar formation, as well as septic shock in severe cases. Purpura fulminans from sepsis requires surgical debridement, skin grafting and even amputation. Photo by @doctordiaries
Hemodynamic stimuli&nonhemodynamic stimuliEffects of sugar on teeth
