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Probiotics, Fecal Transplant Promising in Ulcerative Colitis⠀ ⠀ The probiotic VSL#3 and fecal microbiota transplantation could help induce remission in patients with ulcerative colitis, according to a systematic review and meta-analysis of randomized controlled trials.⠀ ⠀ There is "abundant evidence" that the intestinal microbiome plays an integral role in the pathogenesis of ulcerative colitis, said Mina Fransawy Alkomos, MD, from New York City Health and Hospitals Corporation and Ain Shams University, Cairo.⠀ ⠀ Several studies have shown that strategies to manipulate the microbiome — through diet, probiotics, antibiotics, or fecal microbiota transplantation — might modulate disease activity, but the results are "controversial," he told Medscape Medical News.⠀ ⠀ The problem that we have with the studies is the diversity of probiotics. They used different combinations and amounts of bacteria, and we really don't know which combination is best. ⠀ Credits: @medscape
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