Zunaira saleh1 day ago

Hypothalamic-pituitaryovarian axis

Feedback regulation of the hypothalamic-pituitaryovarian axis in females. Stimulatory effects are shown by plus signs; negative feedback inhibitory effects are shown by minus signs. Estrogens and progestins exert both negative and positive feedback effects on the anterior pituitary and hypothalamus depending on the stage of the ovarian cycle. Inhibin has a negative feedback effect on the anterior pituitary, whereas activin has the opposite effect, stimulating FSH secretion by the anterior pituitary. CNS, central nervous system; FSH, follicle-stimulating hormone; GnRH, gonadotropinreleasing hormone; LH, luteinizing hormone.