Thoracic outlet syndrome (TOS) is a term that refers to three related syndromes involving compression of the nerves, arteries, and veins in the lower neck and upper chest area. This compression causes pain in the arm, shoulder, and neck. Symptoms of TOS vary depending on the type: Neurogenic TOS has a symptom called the. “Gilliatt-Sumner hand,” in which there is severe wasting (weakening) in the fleshy base of the thumb. Other symptoms may include: -Paresthesias (“pins and needles” sensation or numbness) in the fingers and hand -Change in hand color -Cold hands -Dull aching pain in the neck, shoulder, and armpit Venous TOS symptoms may include: -Pallor (paleness) -A weak or absent pulse in the affected arm, which also may be cool to the touch and appear paler than the unaffected arm -Numbness, tingling, aching, or swelling of the arm and fingers -Weakness of the neck or arm Arterial TOS symptoms may include: -Change in color in the hands and fingers -Sensitivity to cold in the hands and fingers -Swelling, heaviness, “pins and needles” sensation or numbness, and poor blood circulation in the arms, hands, and fingers