Myiasis corresponds to an infestation of living tissue by fly larvae. These flies appear most in tropical countries, hot and humid weather, in the rainy summer months. Brazil is a region conducive to the development of the main species of flies that cause miasis in humans, which favors the development of this condition. Oral occurrence of myasis is rare and becomes more common in the elderly, frail, ill, and mentally disabled people. Assessment of the oral cavity of individuals with special healthcare is the primary strategy for the prevention of infestation by fly larvae and other oral pathologies. In addition, adoption of individual and collective protective measures such as weaving the doors and windows of hospitals or home dependents, avoiding exposure of open wounds, necrosate tissue ulcerations, infected eczemas, as well as maintaining good individual and environmental hygiene, and adopting the use of masks in patients without Lip sealing are procedures of utmost importance to prevent the installation of miasis. In this case, the treatment performed was the mechanical removal of the larvae, extraction of the compromised teeth and debridation of necrotic tissue under general anesthesia and administration of systemic antibiotics, as well as medication for pain control and edema.