Symptoms of vascular occlusion include: Pain or discomfort at the site of the blockage. Swelling. Changes to your skin color; red (erythema) to blueish-purple or white spots (blanching). Cool temperature to the affected area of your skin. If you have a vascular occlusion after a dermal filler, you could experience symptoms 12 to 24 hours after your filler procedure. Vascular occlusion is a serious condition that needs medical treatment immediately. If left untreated, vascular occlusion can cause complications that include: Cell and tissue death (tissue necrosis) from a lack of oxygen and blood supply. Organ damage or failure. Heart attack. Stroke.