Signs of an endocarditis infection include: Fever above 100°F (38.4°C). Sweats or chills, particularly night sweats. Skin rash. Pain, tenderness, redness or swelling. Wound or cut that won't heal. Red, warm or draining sore. Sore throat, scratchy throat or pain when swallowing. Sinus drainage, nasal congestion, headaches or tenderness along your upper cheekbones. Persistent dry or a moist cough that lasts more than two days. White patches in your mouth or on your tongue. Nausea, vomiting or diarrhea. Emboli (small blood clots), hemorrhages (internal bleeding) or stroke. Shortness of breath. Poor appetite or weight loss. Muscle and joint aches.