Supplements and Health Disorders In some instances, taking vitamin supplements can trigger a health condition or make an existing health condition worse. Vitamin supplements may contain aspartame, which can cause problems if you suffer from phenylketonuria, or PKU. You should consult with a physician before taking a vitamin supplement if you have kidney disease, the University of Maryland Medical Center warns. If you are a smoker, taking beta carotene can increase your chances of contracting lung cancer. Taking a multivitamin can help alleviate symptoms of fatigue caused by vitamin deficiencies or general poor diet; however, fatigue can be a signal for serious conditions such as thyroid malfunction, anemia or depression. If you don't start feeling better within a few days, try another formula.
Source: https://www.livestrong.com/article/459841-advantages-disadvantages-of-vitamin-supplements/