Complications of deep or widespread burns can include: Bacterial infection, which may lead to a bloodstream infection (sepsis) Fluid loss, including low blood volume (hypovolemia) Dangerously low body temperature (hypothermia) Breathing problems from the intake of hot air or smoke Scars or ridged areas caused by an overgrowth of scar tissue (keloids) Bone and joint problems, such as when scar tissue causes the shortening and tightening of skin, muscles or tendons (contractures)