This video lecture explains all the concepts and information with the help of a slide show elaborated by a lecturer covering the topic of gastric outlet obstruction (GOO). It includes the definition and basic pathology of GOO, its various aetiologies, clinical features, associated biochemical changes, metabolic derangements, investigations required for diagnosis and management strategies commonly employed. Timeline: 0:00 – Introduction 0:37 – Definition of gastric outlet obstruction (GOO) and basic mechanism 3:55 – Aetiologies 9:15 – Clinical features of GOO 14:36 – Biochemical changes 21:23 – Metabolic effects, paradoxical acidic urine and summary of biochemical changes 26:25 – Investigations 27:42 – Management strategies