H2 receptor antagonists are known to reduce the HCl secretions in our stomach. This video discusses on the pharmacology of H2 receptor antagonists and its role in gastric acid secretion, its adverse effects and drug-drug interactions. Timeline: 0:00 Structure and physiology of parietal cells 2:35 H2 receptor blocking receptor 4:45 Types of H2 receptor blockers 7:10 Therapeutic Uses 9:50 Pharmakokinetics 10:36 Adverse Effects 12:35 Drug Drug Interactions 15:55 Revision