The video debates on the use of metformin by diabetic patients and whether is it safe to use as a long term therapy. It also discusses the use of metformin for the purpose of weight loss and also the effects of its monotherapy on lipids. The best part about this video was that it discussed all these with the evidence of research papers. Timeline: 0:00 Introduction 0:18 Metformin Overview 1:08 Metformin Long Term study 2:52 Metformin Weight Loss study 4:05 How it causes weight loss 5:33 Effect of metformin monotherapy on lipids study