Leishmaniasis, a protozoal illness, may either be visceral or cutaneous. However, the treatment is accompanied by serious limitations and leishmaniasis remains as one of the neglected diseases of the world. The treatment approach to the cutaneous form is summarized in the given video. Epidemiology of the disease is also discussed. Timeline: 0.00 Overview 3.05 Treatment recommendations 4.10 Topical options 5.05 Systemic options 10.36 CpG D35- an experimental agent